The Drug Diazepam in Pharmacology Essay Example | Topics and Well Written Essays - 4250 words

The Drug Diazepam in Pharmacology - Essay Example Only paramedics are allowed to use in the management of â€Å"psychostimulant-induced behavioral disturbances† in times of emergency (National Drug Strategy). a. A list of conventional over-the-counter (OTC) medicines, complementary alternative medicines (CAMs) and prescription medicines that are known or suspected to undergo clinically relevant interactions with your profile drug in humans. b. List the source(s) of information you have used and indicate the strength of the evidence (e.g. anecdotal report, clinical case, clinical trial, etc) for each of the interactions that you have identified. Fluconazole is an antifungal that belongs to a group of drugs known as azoles that increases the effects of Diazepam by increasing the levels of Diazepam available in the plasma at any given time. A study conducted by Saari established that Fluconazole increased the level of Diazepam two and a half times thereby increasing the sedative effects of Diazepam. However, the peak plasma concentrations and the pharmacodynamics of Diazepam were not affected (941-999). Voriconazole may inhibit Diazepams metabolism, increasing the risk of adverse effects. In essence, Voriconazole acts the same way as Fluconazole by increasing the levels of Diazepam that are available in the plasma at any given time (Saari 941-999). Therefore, a Diazepam dose should be decreased. Diazepam may possibly increase or decrease phenytoin concentration. The phenytoin concentration should be monitored in case of toxicity and the phenytoin dose should be adjusted as necessary (Australian Medicine Handbook 2011). Enhanced sedation or respiratory and cardiovascular depression may occur if diazepam or other benzodiazepines are combined with drugs that have CNS-depressant properties such as alcohol, antidepressants, sedative antihistamines, antipsychotics, general anesthetics, other hypnotics or sedatives and opioid analgesics.  

Project Managment Essay Example | Topics and Well Written Essays - 1000 words - 2

Project Managment - Essay Example The activities follow a systematic order according to priority needs while coordination among them is profusely maintained. Distributing the tasks among the project staff is important as this will simplify the activities. Once it is done, collection of articles is conducted in order to proceed for sorting them out. Managing articles is more essential than photo collection as articles are undoubtedly the main focus of the magazine. The project manager (PM) should depend on the shortest time. This will make him organize and systematize activities for a successful and early completion of the project. Besides, coordination among the people in the project is important and the PM should motivate his team for it. Both CPA and WBS frameworks are important for a project. However, WBS as a top-down model can assess only from the top management point of view that may ignore activities happened at lower levels. But CPA is adequate in detailing the activities. Circle and arrow diagram also aptly shows the project details. Significance: WBS, OBS and CPA are essential frameworks that help the project manager to explain people involved in the project about the project details. It is the responsibility of the project management team under the PM to do a WBS or CPA. The University magazine project contains top-down and bottom-up approaches for identifying and organizing the project activities. CPA framework studied the critical issues of the project and prioritized the tasks accordingly. WBS and OBS frameworks are adopted in order to break the project down into smaller segments. The University magazine project adopts CPA, WBS and OBS tools for proper planning and scheduling. These tools divide the project into different smaller segments, which results in speedy development of the project. The new project is expected to update the standard of the university magazine to a